Tag Archives: pandemic

CV19 Update Sun 03-29

Posted by xaminmo

CV19 Pandemic Update for 2020-03-29 (Sunday Night).

Most of the numebrs are slowing down vs projections. On 03-24, our growth rate dropped from 135% to 123%, and the last 2 days have been in the 1-teens. TX lags by a couple days in that regard. We are stubborn. There are reports in the worst hit places of reaching a tipping point, but mostly in the highest density areas.

1-Day Projection: WW 736981/34604; PRC 82101/3302; NON 654880/31302; IT 98859/10999; US 145164/2596; TX 3112/35; ME 265/1
1-Day Distancing: WW 736981/34604; PRC 82101/3302; NON 654880/31302; IT 98859/10999; US 144607/2494; TX 2934/37; ME 265/1
2020-03-29 WW 720117/33925; PRC 82122/3304; NON 637995/30621; IT 97689/10779; US 140886/2467; TX 2792/37; ME 253/3
Reminder: PRC numbers are likely 1/6th of the actual due to creamatorium activity.

Social distancing rates have not been updated in a few days, but we are tracking similarly between the two formulae.

Found another error, so the estimates for testing and hospitalization were too high. One of my cells had a $ in it, so it did not change as I added new data.

1-Day US Testing: POS 126,269 NEG 659,435 PEND 70,178 HOSP 23,397 DEAD 2,585
20200329 POS 139,061 NEG 692,290 PEND 65,549 HOSP 19,730 DEAD 2,428

Fewer hospitalized now means fewer dead in 2 weeks.

2020-03-30 (Monday) Projections
1-Day Projection: WW 785,602/37,588; PRC 82,245/3,309; NON 703,357/34,279; IT 103,200/11,592; US 163,395/3,004; TX 3,175/46; ME 303/3
1-Day Distancing: US 164,555/2,970; TX 3,269/44

+1 Day US Testing POS 157,461 NEG 783,890 PEND 74,222 HOSP 24,311 DEAD 2,932

We are definitely slowing down. Look at the April 1 projection trends.

2020-04-01 7-day Projection April 1
7-Day Projection: WW 1,169,645/61,852; PRC 82,134/3,338; NON 1,087,512/58,514; IT 157,313/19,560; US 477,863/6,398; TX 9,131/162
4-day Projection: WW 1,097,956/54,118; PRC 82,357/3,321; NON 1,015,599/50,796; IT 132,717/16,052; US 333,315/5,929; TX 7,263/90; ME 468/5
3-day Projection: WW 1,017,269/50,218; PRC 82,428/3,321; NON 934,841/46,897; IT 124,403/14,738; US 278,237/5,179; TX 5,427/83; ME 426/5

The distancing formula has been tracking more consistently over the longer term.
7-Day Distancing: US 232,880/4,603; TX 5,875/72
4-day Distancing: US 237,600/4,513; TX 5,003/68
3-day Distancing: US 231,486/4,464; TX 4,761/68

Hospitalization rates are going down, while positive and total testing rates are going up.
7-Day US Testing: POS 134,035 NEG 728,160 PEND 100,028 HOSP 68,262 DEAD 4,770 Overrun: 04-06 335k
4-Day US Testing: POS 150,376 NEG 785,328 PEND 83,576 HOSP 64,012 DEAD 5,886 Overrun: 04-06 342k
3-Day US Testing: POS 164,152 NEG 817,199 PEND 77,376 HOSP 44,840 DEAD 4,592 Overrun: 04-09 408k

I am just giving the general overrun rate above. That is typically within 1 day of when the TX projections look bad, and tracking kinda bad vs super bad is a lot of effort.

Testing rates slowed a little, but not much.

Our mortality rate keeps climbing. 144, 155, 167, 175. TX just started the climb, 122 yesterday, and 133 today. Probably the spring break people. Average is 6 days to onset and 14 days from onset to death for those who do not survive.

Some good research is going on that promises to improve mortality rates.

Inflection point for outbreaks with an R0 of 2.2 is 60% of the population becoming immune. Divide that by whatever you think our detection rate is. I think we get about 38%, so maybe 75m people in the US showing as confirmed.

Social distancing data lags by 3-5 days. Statistics lag by 1 day. Detection lags by 9-12 days. Impact delay of SD on Confirmations MAY BE 9 days, or it may be longer. The correlation is hard to suss out, but it may be that it will become more evident as we get more days of data.

Spreadsheet is updated, and downloadable here:
https://drive.google.com/file/d/1vocCN445AZyVBBLsv0kJR8ZDP9DM0UST/view


Pandemic Update March 27

Posted by xaminmo
CV19 Pandemic Update for 2020-03-27 (Friday)’s final numbers. I waited long enough, it is almost time for another update. But, I got some sleep. That helped me feel better. Also, it’s Erica’s birthday!
 
03-27 Friday
1-Day Projection: WW 601509/27192; PRC 81903/3297; NON 519605/23895; IT 87309/8995; US 106851/1552; TX 1988/29
1-Day Distancing: WW 601509/27192; PRC 81903/3297; NON 519605/23895; IT 87309/8995; US 103554/1554; TX 1971/27
Actual Numbers: ww 593291/27198; PRC 81897/3296; NON 511394/23902; IT 86498/9134; US 101657/1581; TX 1937/26
 
1=Day US Testing: POS 89,618 NEG 486,863 PEND 66,880 HOSPITAL 13,923 DEAD 1,471
Actual Numbers: POS 99,413 NEG 527,220 PEND 60,094 HOSPITAL 13,718 DEAD 1,530
 
The numbers are really close to estimates, except Italy had a few more deaths. Almost everything else was on par or a little lower than estimated.
 
 
2020-03-28 Saturday 20:00ish
1-Day Projection: WW 666020/30928; PRC 82012/3301; NON 584008/27627; IT 92840/10156; US 123266/2067; TX 2400/32
1-Day Distancing: WW 666020/30928; PRC 82012/3301; NON 584008/27627; IT 92840/10156; US 123859/2000; TX 2390/33
1-Day US Testing: POS 107,568 NEG 561,770 PEND 59,784 HOSPITAL 23,397 DEAD 2,585
 
I only include the numbers for PRC because it fits my chart. I am sure thei are bogus, since their funeral omes are cremating thousands of bodies per week. Dear China, I respect honesty, not obedience. I know, I am not 10,000 years old. I know, keeping people from panicking is important.
 
 
2020-04-01 7-day Projection
7-Day Projection: WW 1169645/61852; PRC 82134/3338; NON 1087512/58514; IT 157313/19560; US 477863/6398; TX 9131/162
7-Day Distancing: WW 1169645/61852; PRC 82134/3338; NON 1087512/58514; IT 157313/19560; US 232880/4603; TX 5875/72
7-Day US Testing: Positive: 134,035 Negative: 728,160 Pending: 100,028 Hospitalized: 68,262 Dead: 4,770 Overrun: 04-06 295-335k
 
For April 1, we are trending to have more confirmed (mostly from Italy), fewer dead (more than the testing stat dead though), fewer in the hospital, and a lot more tests run. We are clearing 110k tests per day.
 
The US testing chart looks like hospital overrun may be April 6 (32% of US hospital beds).
 
Texas projections move one more day further out on every estimate.
04-07 29k TEXAS ICU OVERRUN STAGE 1
04-06 36k TEXAS VENT OVERRUN STAGE 1
04-13 146k TEXAS ICU STG3
04-14 178k TEXAS VENT STG3 & Hosp STG1
04-17 400k may be the inflection point for Texas if 14% like China, but our death rate is lower than theirs or the world.
04-18 532k TEXAS HOSP STG3
04-21 1.2m Inflection point for R0 of 2.2 is 60% with detection rate of 39.08
 
The distancing formula overrun estimates are pulled way back closer to the others, because social distancing got worse again. It is only -20% right now.
04-11 2929 TEXAS ICU OVERRUN STAGE 1
04-12 1787 TEXAS VENT OVERRUN STAGE 1
04-20 2929 TEXAS ICU OVERRUN STAGE 3
04-21 1787 TEXAS VENT OVERRUN STAGE 2
04-21 26633 TEXAS HOSPITAL OVERRUN STAGE 1
04-25 400k may be the inflection point for Texas if 14% like China, but our death rate is lower than theirs or the world.
04-27 4550 TEXAS VENT OVERRUN STAGE 3
04-28 26633 TEXAS HOSPITAL OVERRUN STAGE 2
05-01 47441 TEXAS HOSPITAL OVERRUN STAGE 3
05-02 1.2m Inflection point for R0 of 2.2 is 60% with detection rate of 39.08
 
 
Here are the milestones from 04-23 data for comparison to track our progress flattening the curve:
04-06 33k TEXAS ICU OVERRUN STAGE 1
04-07 45k TEXAS VENT OVERRUN STAGE 1
04-10 150k TEXAS VENT/ICU STG2 & Hosp STG 1
04-13 366k TEXAS VENT/ICU STG3 & Hosp STG 2
04-15 660k TEXAS Hosp STG 3
 
Milestones are based on guesstimates.
TX 28.7m pop; 2.9 beds per 1000 in TX (83230); 32% unoccupied (26633) / 11% are ICU (2929); 6.7% ventilators (1787); 10% limited function ventilation (2663) / 5-15% conf need hosp(532k-177k @ overrun); 2-10% ICU (29k-146k); 1-5% need vent (36k-178k)
 
Testing has ramped up substantially, every 2 days another 20k per day. We are at 110k per day as of 2020-03-28 16:00 EDT.
 
Our mortality rate is still about a third of the rest of the world, with TX going down, and the US going up just a little today.
 
Inflection point for outbreaks with an R0 of 2.2 is 60% of the population, not 60% of the confirmed cases. If we are catching a third of the cases, then uncontrolled, exponential climb would stop when confirmed cases were 20% of the population. If we are catching a 6th, then 10%.
 
Social distancing data lags by 3 days. Statistics lag by 1 day. Detection lags by 9-12 days. Impact delay of SD on Confirmations MAY BE 9 days, or it may be longer. The correlation is hard to suss out, but it may be that it will become more evident as we get more days of data.
 
Spreadsheet is updated, and downloadable here:

Social Distancing Dashboard

Posted by xaminmo
This site uses anonymous mobile phone data to calculate the change in miles traveled, and the change in number of mobile phone encounters. It is an earlier predictor of how well social distancing is working, without having to wait 12 days for the confirmed cases stats to change, nor worry about changes in testing frequency or methodology.
 
It’s really a green-light instantaneous dashboard kind of thing. They don’t expose trending data, or even numerical data, so you cannot chart, trend, or predict off of this.
 

CV19 no big deal

Posted by xaminmo
A good question I saw and responded to is “Hardly anyone is sick, and hardly anyone has died. Why is everyone all panicky about CV19? What’s missing?”
 
TLDR: It spreads exponentially, and while you have no symptoms. Listen to the experts if you don’t understand. Don’t be a party to manslaughter.
 
NARRATIVE: The missing part is that it’s an exponential spread. It’s like the old puzzle, there’s one lily pad on a pond, and every day, each lily pad becomes two. It takes 30 days to cover the pond. When is the pond half covered? 29 days.
 
Today, the absolute numbers look very mild right now, and that’s what we like. We want them to stay mild, but any action we take will not have an effect for 12 days. Also, number reporting lags by 1 day. 13 days before the end looks like just any other day in paradise. We’re not doubling every day. We’re doubling every 2.2 days.
 
For the US, we are 10 days from overloading hospital capacity, and 14 days from overloading even reserve, crappy capacity. When we overload the hospital capacity, the death rate quadruples. That’s why it became such a panic.
 
Luckily, the declaration of pandemic was on the 11th, which just started to show up in the numbers yesterday. We’ll know by late Thursday if the declaration of national emergency made an impact. The goal is to keep the number of people in the hospital below the threshold where a lot of extra people die. Right now, that looks so far off, but if we didn’t drastically slow the spread, that would start to look grim for the worst survivable cases around April 5, and by April 15 would be just letting the really sick asphyxiate. I say “didn’t” rather than “don’t” because the time to take action has already passed.
 
It’s easy to ignore when 85% of the people infected simply are not counted, and when only 10% of the counted people are at risk of dying from a hospital overload. However, that amounts to 2-5 million people in the US potentially dying from this. With that many, chances are one of them would be a close friend or family member. If it happens to you, then you would definitely care, and you would not care that it was because a bunch of people didn’t understand exponential math.
 
The panic is because a bunch of us care even when it’s not someone close to us, or we can see that it could happen to us. There are a lot of asymptomatic carriers, spreading the disease. So “I feel fine, I don’t need to quarantine” has already lead to deaths, and will lead to many more deaths.
 
It wouldn’t be God’s Will, or bad luck. It would be a willful choice of people to ignore the experts because the non-experts didn’t understand, and therefore decided the experts were not actually experts. Reckless action leading to the death of others is called manslaughter, and negligent action leading to death is called negligent homicide. Purposefully infecting someone would be called murder.
 
Lag times per Feb 7 study in JAMA from Wang et al:
Median time from first symptom to dyspnea was 5.0 days
to hospital admission was 7.0 days
to acute respiratory distress syndrome was 8.0 days.
For survivors, the median hospital stay was 10 days.
https://jamanetwork.com/journals/jama/fullarticle/2761044
 
Lag times per Jan 22 report by China National health:
Median days from first symptom to death were 14 (range 6-41)
70 year old or above (11.5 [range 6-19] days)
below 70 year old (20 [range 10-41] days.
https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.25689?af=R
 
The average is 12 days to show up in the stats, and 20 days start to finish, so that’s what most stats focus on. Policy changes consistently take 12 days to show up in the stats. I’m not sure where that first started, but you can look at the raw numbers and see it. It is self evident.

SARS-2 March 24 Update

Posted by xaminmo

First, the update:

03-24 Tuesday
1-day Projection: WW 425953/18600; PRC 81595/3283; NON 346031/15382; IT 69104/6744; US 57310/731; TX 916/10
Actual Numbers: WW 417966/18615; PRC 81591/3281; NON 336375/15334; IT 69176/6820; US 53740/706; TX 955/12

03-25 Wednesday
1-day Projection: WW 461807/21005; PRC 81686/3288; NON 381238/17782; IT 74856/7654; US 66137/903; TX 1203/16

Infection spread appears to be reducing in US and TX, even though TX was above projections for yesterday.
US shows 134% instead of 135%, and the last 3 days were 130%, 131%, and 123%.
TX shows 135% instead of 147%, and the last 3 days were 108%, 121%, and 126%.

This implies that the declaration of pandemic may have had positive effect.

The numbers from tonight or tomorrow will start reflecting any changes caused by the declaration of national emergency.

Milestones would have pushed out a day, but my methodology was poor. I now show the number for the condition in the left of the note, not the estimated number for that day. Also, I dropped stage 2 here, and just show worst case reserve (smallest number) and best case reserve (largest number). I do not have proper numbers to separate stage 1 (over standard) vs stage 2 (over minimum reserve).

04-05 29k TEXAS ICU OVERRUN STAGE 1
04-06 36k TEXAS VENT OVERRUN STAGE 1
04-10 146k TEXAS ICU STG3
04-11 178k TEXAS VENT STG3 & Hosp STG1
04-14 400k may be the inflection point for Texas
04-15 532k TEXAS HOSP STG3

Milestones are based on guesstimates, because the exact number of ICU beds and placement of ventillators is proprietary data that is hard to find and confirm. My estimates are based on: TX 28.7m pop; 2.9 beds per 1000 in TX (83230); 32% unoccupied (26633) / 11% are ICU (2929); 6.7% ventilators (1787); 10% limited function ventilation (2663) / 5-15% conf need hosp(532k-177k @ overrun); 2-10% ICU (29k-146k); 1-5% need vent (36k-178k)

Testing infrastructure may fail before the inflection point, leading to a false decrease in numbers reported. If that happens, we may not numerically reach the inflection point, which is 60% of the population for R0 of 2.2. Remember, we only confirm 12-15% of the actual cases, as many are mild or even asymptomatic, but are still infectious to others.

I expect these to move further out each of the next few days, and then it will probably look like it levels off a bit for several days before reducing further.

We are not out of the woods. Hospital usage is 1-4 weeks. Average infection course is 20 days with no hospitalization, but once people are bad enough to need O2 or ventilation, it takes longer to recover well enough to not need it anymore.  If we were to fall to 112% today (unrealistic extreme) and stay there, the milestone dates become 04-23, 04-25, 05-07, 05-09, 05-16, 05-18. That spreads out enough that we may gain an extra couple of days on each due to early cases resolving (people do not stay in the hospital forever).

The current milestones for the US, since TX is about 9% of the US:
03-31 29k -> 322k US ICU OVERRUN STAGE 1
03-31 36k -> 400k US VENT OVERRUN STAGE 1
04-05 146k -> 1622k US ICU STG3
04-06 178k -> 1977k US VENT STG3
04-08 400k -> 4444k US inflection point
04-09 532k -> 5800k US HOSP STG 2

These are MUCH more fuzzy, since it is not exactly 9%, and ICU, Vent and bed capacities vary. That adds 1-2 days uncertainty. This also will be affected by any changes in the numbers as discussed above.

Here are the milestones from 04-23 data for comparison to track our progress flattening the curve:
04-06 33k TEXAS ICU OVERRUN STAGE 1
04-07 45k TEXAS VENT OVERRUN STAGE 1
04-10 150k TEXAS VENT/ICU STG2 & Hosp STG 1
04-13 366k TEXAS VENT/ICU STG3 & Hosp STG 2
04-15 660k TEXAS Hosp STG 3

NOTE that the very first milestone was 04-02 based on 570 ICU beds, and was abandoned as a predictor.

When testing and behavior are nonchanging:
Model is +/- 25% per week
That is +/- 1.5 days for stage 1
That is +/- 2.5 days for stage 2
That is +/- 3.5 days for stage 3

Inflection point for R0 of 2.2 is 60%.
Current reporting rate is 12-15%.
Assuming we keep testing by same criteria, the Tx inflection point is 400k confirmed.
We may not reach this numerically due to testing/infrastructure failure.
eg, we may reach stage 3 while our confirmed rate is much lower, but still around the same days.

This is all bistromath, and both reporting rates, and trends are changing daily at this point.

Also note that the numbers lag by up to 24 hours based on reporting systems.

Also Also note that it still takes around 12 days for action changes to affect trends, since people infected today will not be detected for a while.

Also Also Also note that there are many people who have NO symptoms at all, but are still infecting others. This, along with poor testing, explains the 12-15% confirmation rate.

https://drive.google.com/file/d/1vocCN445AZyVBBLsv0kJR8ZDP9DM0UST/view


Overrun Planning

Posted by xaminmo

Stats for Sunday, Monday, and predictions for Tuesday, and Texas hospital overruns.

03-22 Sunday

  • 7-day Projection: WW 262771/11285; PRC 81266/3324; NON 259371/14696; IT 78550/8986; US 25567/280; TX 521/21. plus or minus 25%.
  • 1-day Projection: WW 340729/14895; PRC 81360/3265; NON 260988/11728; IT 61049/5774; US 34015/386; TX 857/5.
  • Actual Numbers: WW 335955/14632; PRC 81397/3265; NON 254558/11367; IT 59138/5476; US 33272/417; TX 627/8

03-23 Monday

  • 1-day Projection: WW 370630/16503; PRC 81489/3271; NON 290297/13301; IT 65275/6215; US 43432/566; TX 627/13. TX Deaths is Still early and erratic
  • Actual Numbers: WW 378287/18600; PRC 81496/3274; NON 296791/13223; IT 63927/6077; US 43667/552; TX 758/9. IT is slowing, which is good. JHU new dataset.

03-24 Tuesday

  • 1-day Projection: WW 425,953/18,600; PRC 81,595/3,283; NON 346,031/15,382; IT 69,104/6,744; US 57,310/731; TX 916/10
  • Actual Numbers: To be determined.  Infection spread for US is fluctuating slightly.

The following major milestones assume no gross change in testing rates nor confirmed infection rates.  Stage 1 is over standard capacity.  Stage 2 is over worst case reserve capacity.  Stage 3 is over best case reserve capacity.  This does not cover additional production, but does cover identified lower-function and out-of-date equipment from federal, military, and major hospital stockpiles.  At Stage 1, alternative locations are getting converted for use by patients, such as closed medical buildings.  At stage 2, we’re relying on medical and nursing students as front-line caregivers, and MASH style pop-up tent hospital expansions start getting deployed where possible. At stage 3, we’re draping parking garages, and getting scouts with first-aid badges to help.  Elderly or anyone with comorbidities will be comforted, but won’t get access to mechanical ventilation.  Only those with the best chance of survival with, and a high risk of death without, would get advanced care.

  • 04-05 33k TEXAS ICU OVERRUN STAGE 1 / 28.7m pop; 2.9 beds per 1000 (83230); 32% unoccupied (26633) / 11% are ICU (2929); 6.7% ventilators (1787) and 10% limited function ventilation (2663) / 5-15% conf need hosp(532k-177k @ overrun); 2-10% ICU (29k-146k); 1-5% need vent (36k-178k)
  • 04-06 45k TEXAS VENT OVERRUN STAGE 1 / 28.7m pop; 2.9 beds per 1000 (83230); 32% unoccupied (26633) / 11% are ICU (2929); 6.7% ventilators (1787) and 10% limited function ventilation (2663) / 5-15% conf need hosp(532k-177k @ overrun); 2-10% ICU (29k-146k); 1-5% need vent (36k-178k)
  • 04-10 150k TEXAS VENT/ICU STG2 & Hosp STG 1 / 28.7m pop; 2.9 beds per 1000 (83230); 32% unoccupied (26633) / 11% are ICU (2929); 6.7% ventilators (1787) and 10% limited function ventilation (2663) / 5-15% conf need hosp(532k-177k @ overrun); 2-10% ICU (29k-146k); 1-5% need vent (36k-178k)
  • 04-13 366k TEXAS VENT/ICU STG3 & Hosp STG 2 / 28.7m pop; 2.9 beds per 1000 (83230); 32% unoccupied (26633) / 11% are ICU (2929); 6.7% ventilators (1787) and 10% limited function ventilation (2663) / 5-15% conf need hosp(532k-177k @ overrun); 2-10% ICU (29k-146k); 1-5% need vent (36k-178k)
  • 04-15 660k TEXAS Hosp STG 3 / 28.7m pop; 2.9 beds per 1000 (83230); 32% unoccupied (26633) / 11% are ICU (2929); 6.7% ventilators (1787) and 10% limited function ventilation (2663) / 5-15% conf need hosp(532k-177k @ overrun); 2-10% ICU (29k-146k); 1-5% need vent (36k-178k)

The inflection point for R0 of 2.2 is 60%. Current reporting rate is 12-15%. Assuming we keep testing by same criteria, the Tx inflection point is about 400k confirmed. We may not reach this numerically due to testing/infrastructure failure. eg, we may reach stage 3 while our confirmed rate is much lower, but still around the same day, and still around the same number of actual infected.  Also, there are different groups between spreaders and isolators.  I don’t know the balance of those two groups. They could be 20/80 or 50/50.

Barring major changes, the model is +/- 25% per week.  That is +/- 1.5 days for stage 1. That is +/- 2.5 days for stage 2. That is +/- 3.5 days for stage 3.

If the Pandemic declaration helped, then 03-24 will be at least 2% low for US and TX. If the Emergency declaration helped, then 03-25 will be at least 2% low for US and TX.  Either of those should show a continual downward trend.  We have had a lot of people ignoring expert and government recommendations, so I do not expect an abrupt change.

If we did abruptly fall to, say, 112% on 03-24 and stay there, then Stage 1 starts April 23-26; then Stage 2 starts May 7-11; Stage 3 may never happen due to average disease cycle of 20 days, and ICU cycle of 30 days.  This would be a dream scenario, and is unlikely.  More likely to see a 5% drop several days in a row.  It’s unlikely to see the clam-down go below 110% until it looks really bad (and then it’s too late).

Texas is about 9% of the US capacity and slightly more capacity than average.  Look for 11x numbers in the US column for similar problems.

  • 33k -> 363k on 03/30 Stage 1 ICU
  • 45k -> 495k on 03/31 Stage 1 Vent
  • 150k -> 1650k on 04/04 Stage 2 / Stage 1 Hosp
  • 366k -> 4026k on 04/07 Stage 3 / Stage 2 Hosp
  • 660k -> 7260k on 04/09 Stage 3 Hosp

112% projections:

  • 112% ICU Stage 1 is 04/10
  • 112% Vent Stage 1 is 04/12
  • 112% V2 / Hosp Stage 1 is 04/23
  • 112% V3/H2 is 05/01
  • 112% H3 is 05/06
  • 112% numbers are +/- 3, 5, and 7 days.

This is all bistromath, and really, anything more than a week out is just guesswork. A lot can change in a week, and I’m expecting substantial changes over the next 3 days based on the activities 10-14 days ago.

The Spreadsheet has been updated. JHU replaced some data sources, so it was a little annoying, and a little more manual entry.

https://drive.google.com/file/d/1vocCN445AZyVBBLsv0kJR8ZDP9DM0UST/view


Projection Spreadsheet

Posted by xaminmo

Google link is https://drive.google.com/file/d/1vocCN445AZyVBBLsv0kJR8ZDP9DM0UST/view View/comment only. I don’t know what broke yet, or if everything works right.


Tsunami

Posted by xaminmo

I have been maintaining projections on omnitech.net/blog and fb.com/xaminmo .

Basically, it is time to hide from society right now. There are a lot of people still spreading it because it is their right to be free. If you get it now, there will be no resources to help you if you get very sick.

Projections may change by Wednesday, since that is 12 days after the national emergency was declared. If we cut our spread in half, then we get almost an extra week of respite.

Except, I know groups of people who were congregating for public meals as recently as Wednesday, and group exercise just Friday. 6 feet at 14mph is not enough. I don’t have the ability to get people to trust me. Either they see, or they don’t. Plenty actively disbelieve. It’s core to their being to believe exactly opposite of me.

We got complacent, because we’re “not like Italy. Look, they are older, and we were infected sooner. We’re so much better, and our death rate is lower.”

Italy started at +25% per day, and brought it down to +12% per day.

The US started at +5-10%, but for weeks has been spreading at +35% per day. Texas, my state, has to do it bigger. We’re spreading at +47%.

So, April 2, Texas ICU reserve capacity is overrun. A week later, all Texas hospital reserve capacity is overrun. I don’t know where in there we run out of trained medical professionals and supplies to treat safely.

If we did a great job when the pandemic was declared, we get 4-6 more days. A week prior, it will look like a normal day, a little busy, and probably still no toilet paper.

I wish it were not so, but the window of opportunity to change this course is almost closed, and we seem to be accelerating towards it, not slowing.

A tsunami is coming, and we have not even felt the tremor yet.


SARS2 not from a lab

Posted by xaminmo

Two bits of info indicating extremely unlikely that this was engineered in a laboratory: A) Computer models show the binding function would be very poor for how it binds; B) The core code of the virus matches animal versions, not versions known to make humans sick.

Here's why: SARS-CoV-2 is very closely related to the virus that causes severe acute respiratory syndrome (SARS), which fanned across the globe nearly 20 years ago. Scientists have studied how SARS-CoV differs from SARS-CoV-2 — with several key letter changes in the genetic code.

Yet in computer simulations, the mutations in SARS-CoV-2 don't seem to work very well at helping the virus bind to human cells. If scientists had deliberately engineered this virus, they wouldn't have chosen mutations that computer models suggest won't work.

https://www.livescience.com/coronavirus-not-human-made-in-lab.html

This evidence for natural evolution was supported by data on SARS-CoV-2’s backbone – its overall molecular structure. If someone were seeking to engineer a new coronavirus as a pathogen, they would have constructed it from the backbone of a virus known to cause illness. But the scientists found that the SARS-CoV-2 backbone differed substantially from those of already known coronaviruses and mostly resembled related viruses found in bats and pangolins.
https://www.scripps.edu/news-and-events/press-room/2020/20200317-andersen-covid-19-coronavirus.html


US must be testing

Posted by xaminmo

Must have been a lot of testing. US count doubled yesterday. Everything except China showed up as higher than projected infection rates. US and TX death rates are still low. Italy death rates are still high. Here are the numebers for 2020-03-19. Today’s numbers release sometime in the next 2-3 hours.

Where     Cases   Deaths  Recovered  Mort/A   Mort/R
World   242,713    9,867     84,962   4.07%   10.41%
China    81,156    3,249     70,535   4.00%    4.40%
NonPRC  161,557    6,618     14,427   4.10%   31.45%
Italy    41,035    3,405      4,440   8.30%   43.40%
US       13,680      200        108   1.46%   64.94%
Texas       260        1          0   0.38%  100.00%

Today’s numbers release sometime in the next 2-3 hours. The estimates for today’s numbers (03-20) are 274102/11148 WW; 81210/3257 PRC; 195048/7975 NON; 47150/3893 IT; 24034/339 US; 391/8 TX

Data source is Johns Hopkins University repository here:
https://github.com/CSSEGISandData/COVID-19/tree/master/csse_covid_19_data/csse_covid_19_time_series

Projections are just Excel, divide today by yesterday to get the change day to day, then use a 7-day average to guess what tomorrow might be, and do that again for each row.

In the US, first and second hand reports show that people are tested for seasonal influenza first, and if they test positive, they are not tested for SARS-2. This is conserve the the limited number of tests. It’s less likely for people to have both COVID19 and influenza at the same time. This may change as testing capability increases. According to Trump, Rosche, Quest, Labcorp, and Wal-Mart may be rolling out rapid testing capability starting in April.

In the US, it looks like the confirmed cases are about 13% of the actual infected. The actual death rate for non-overwhelmed places tends to be about 4.5% of the confirmed cases, when there’s ~14% testing (PRC and WW average).

The real mortality rate will therefore be that much less, which puts it in the same order of magnitude as seasonal influenza, but without the ability for people to get vaccinated, and a higher infection rate due to longer infectious incubation period.